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. 2022 Mar 15;43(9):2923–2935. doi: 10.1002/hbm.25826

TABLE 5.

Sex affected functional connectivity of insula subregions

Seed regions Abnormal regions Peak MNI coordinate (x y z) Peak intensity Cluster size (voxels)
dIa.L ORBinf.R 45 39 −9 5.2359 47
PUT.R 27 18 −6 5.2555 32
ORBsupmed.L −6 48 −6 5.8535 43
PCUN.R 6 −60 30 5.419 50
dIa.R ORBinf.R 42 24 −15 5.4508 35
ORBsupmed.R 3 63 15 5.6003 42
PCUN.R 6 −69 27 5.7296 116
dId.L MTG.L −57 −15 −21 5.6649 57
MTG.R 63 −12 −18 5.9344 35
ORBinf.R 45 39 −9 5.5673 52
ORBsupmed.L −6 51 −6 5.7225 42
dId.R ORBinf.R 57 33 −6 5.6034 49
vId_vIg.R Cbe9.L −6 −48 −51 −6.8828 67
ORBinf.R 57 30 −6 5.9174 41
CUN.R 3 −90 9 −7.023 48

Note: All the regions with cluster size ≥30 voxels survived at a threshold of corrected p < .001, FDR correction.

Abbreviations: Cbe9, cerebellum 9; CUN, cuneus; dIa, dorsal agranular insula; dId, dorsal dysgranular insula; L, left; MTG, middle temporal gyrus; ORBinf, orbital part inferior frontal gyrus; ORBsupmed, medial orbital superior frontal gyrus; PCUN, precuneus; PUT, putamen; R, right; vId_vIg, ventral dysgranular and granular insula.