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. 2022 May 6;13:897413. doi: 10.3389/fimmu.2022.897413

Table 2.

Clinical characteristics of the studies and control groups.

Group p-Value
C HS IS ANOVA HS vs. C IS vs. C IS vs. HS
n = 30 n = 15 n = 15
Sex Male
n (%)
15 (50) 7 (46.66) 7 (46.66) ND
Female
n (%)
15 (50) 8 (53.33) 8 (53.33)
Age * 63.07 ± 10.74
[59.06 - 67.08]
64.53 ± 8.123
[60.04 - 69.03]
61.6 ± 12.97
[54.42 - 68.78]
0.7586 0.9032 0.9032 0.7377
Education Primary
n (%)
2 (6.66) 1 (6.66) 1 (6.66) > 0.9999
Vocational
n (%)
15 (50) 7 (46.66) 6 (40)
Secondary
n (%)
9 (30) 6 (40) 6 (40)
University
n (%)
4 (13.33) 1 (6.66) 2 (13.33)
Place of residence Urban center
n (%) *
10 (33.33) 6 (40) 7 (46.66) > 0.9999
Small town
n (%) *
8 (26.66) 4 (26.66) 3 (20)
Rural area or small village
n (%) *
12 (40) 6 (40) 6 (40)
Cognitive and physical functional status
ACE III * 97.47 ± 1.48
[96.91 - 98.02]
69.47 ± 25.04
[55.6 - 83.33]
61.47 ± 22.33
[49.1 - 73.84]
< 0.0001 < 0.0001 < 0.0001 0.3929
BI* 20 ± 0
[20 - 20]
10.73 ± 4.166
[8.426 - 13.04]
10.47 ± 3.62
[8.46 - 12.47]
< 0.0001 < 0.0001 < 0.0001 0.9615
FIM* 125.2 ± 0.68
[125 - 125.5]
81.8 ± 34.16
[62.88 - 100.7]
83.47 ± 33.48
[64.93 - 102]
< 0.0001 < 0.0001 < 0.0001 0.9798
BBS* 55.53 ± 0.51
[55.34 - 55.72]
31.53 ± 18.91
[21.06 - 42.01]
28.47 ± 17.6
[18.72 - 38.21]
< 0.0001 < 0.0001 < 0.0001 0.7899
Comorbidities
Diabetes n (%) 13 (43.33) 7 (46.66) 6 (40) > 0.9999
Hypertension n (%) 16 (53.33) 8 (53.33) 8 (53.33) > 0.9999
Arteriosclerosis n (%) 13 (43.33) 7 (46.66) 7 (46.66) > 0.9999
Limb thrombosis n (%) 4 (13.33) 2 (13.33) 2 (13.33) > 0.9999
Atrial fibrillation n (%) 5 (16.66) 2 (13.33) 3 (20) > 0.9999
Drugs
< 5 drugs/day n (%) 16 (53.33) 7 (46.66) 6 (40) > 0.9999
≥ 5 drugs/day n (%) 14 (46.66) 8 (53.33) 9 (60)

Results were analyzed using ANOVA analysis of variance followed by Tukey’s post hoc test; ACE III, Addenbrooke’s Cognitive Examination III; BBS, the Berg Balance Scale; BI, Barthel Index; C, Control group (n = 30); FIM, functional independence measure; HS, hemorrhagic stroke group (n = 15); IS, ischemic stroke group (n = 15); n, number of patients; ND, no data.

*Expressed as mean ± standard deviation (SD) [95% confidence interval (95% CI)].