Table 5.

Summary of PET findings for studies focused on stroke.

References	Explicit neurologic symptoms	RGD-based tracer accumulation				RGD-based tracer changes according to time after the event	Correlation between RGD uptake and stroke size	Other modalities used to determine the infarct zones	Uptake pattern	Histological correlates
		Days after the event	Positive number	SUV values	Negative number
Choi et al. (22)	13/17 (per lesion analysis)	1–422 days	8/17 (per lesion analysis)	No SUV value reported, lesion to control ratios 3.9 ± 4.09	9/17 (per lesion analysis)	No serial assessment. Higher tracer accumulation in the recent infarct group (<30 days after the event)	NR	Brain MRI/99mTc-HMPAO perfusion	Higher tracer accumulation in the three lesions with hyperperfusion as compared with the other lesions (P = 0.033)	NR
Sun et al. (16)	16/16 patients	4–13 years (n = 16)	8/16	SUVpeak 0.46 ± 0.29, SUV ratios 3.29 ± 1.09, with peak uptake 2 weeks after the event	8/16	Reduced intensity (n = 1) or disappearance (n = 1) on second PET/CT scans	In patients scanned 13th−26 days after the event (r = 0.835, P = 0.003)	Brain MRI/brain 18F-FDG PET/CT	Punctate multifocal form	NR
		3 months (n = 2)	1/2	SUVpeak 0.16 (n = 1)	1/2			Brain 18F-FDG PET/CT

NR, not reported.