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. 2021 Jul 12;46(3):396–407. doi: 10.1016/j.jgr.2021.07.004

Fig. 2.

Fig. 2

G-Rh2 suppresses the migration and invasion of CRC cells. (A) and (B) Wound-healing assay in HCT15, HCT116, and DLD1 cells following treatment with G-Rh2 for 12 and 24 h, respectively (scale bar, 250 μm). (C) and (D) The migration abilities of HCT15, HCT116, and DLD1 cells were determined by transwell assay after treatment with different concentrations of G-Rh2 for 48 h (scale bar, 128 μm). (E) and (F) The invasion abilities of HCT15, HCT116, and DLD1 cells were determined using transwell assay after treatment with different concentrations of G-Rh2 for 48 h (scale bar, 128 μm). (G) Western blot analysis showing the expression of N-cadherin, vimentin, and E-cadherin in CRC cells after treatment with different concentrations of G-Rh2 for 48 h. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 versus control.