Table 1.
Group | Prostate weight (g) | Prostate ratioa (mg/100 g of BW) |
---|---|---|
Control | 0.52 ± 0.03d | 0.11 ± 0.01d |
BPH | 0.96 ± 0.05a | 0.22 ± 0.01a |
25 | 0.94 ± 0.07a | 0.21 ± 0.02a |
50 | 0.90 ± 0.04ab | 0.21 ± 0.01a |
100 | 0.79 ± 0.03bc | 0.18 ± 0.01b |
200 | 0.76 ± 0.04c | 0.18 ± 0.01b |
Finasteride | 0.59 ± 0.03d | 0.14 ± 0.01c |
Control: corn oil oral intake + corn oil injection; BPH: corn oil oral intake + testosterone injection; 25: TP injection + KGC11o (25 mg/kg/day); 50: 50 mg/kg KGC11o + testosterone injection; 100: 100 mg/kg KGC11o + testosterone injection; 200: 200 mg/kg KGC11o + testosterone injection; finasteride: 10 mg/kg finasteride + testosterone injection. For all the groups, testosterone was used at 3 mg/kg body weight/day. Different letters show a significant difference at p < 0.05, as determined by Duncan's multiple range test.
Prostate ratio: prostate weight (mg)/body weight (mg) x 100 (g).