TABLE 1.
Baseline characteristics | Results | |
---|---|---|
Sex ratio (male:female) | 0.66 (8:12) | |
Educational level | Primary | 3 |
Secondary | 5 | |
Superior | 12 | |
Current age (years) [min; max] | 34 ± 7.5 [20; 45] | |
Mean age of onset (years) [min; max] | 26 ± 6 [17; 35] | |
Mean disease's duration (years) [min; max] | 8 ± 5.5 [2; 23] | |
Type of the first relapse | Motor | 11 |
Visual | 2 | |
Cerebellar | 2 | |
Brainstem | 5 | |
Diagnosis's delay (years) | 1 ± 1.8 [0; 6] | |
First‐line disease‐modifying therapy | Beta‐1b interferon (Betaferon) | 8 |
Beta‐1a interferon (Rebif) | 3 | |
Beta‐1a interferon (Avonex) | 8 | |
Induction therapy | 1 | |
Reasons to switch to second‐line therapy | Poor adherence to treatment | 6 |
Mean AAR [min; max] | 1.6 ± 1 [0; 4] | |
Increase of number of lesions in MRI control | 6 | |
Presence of active lesions in MRI control | 4 | |
Side effects of treatment | 2 | |
Mean baseline‐EDSS [min; max] | 3.5 ± 2.5 [1; 6] |
Abbreviations: AAR, annual atrophy rate; EDSS, Expanded Disability Status Scale; MRI, magnetic resonance imaging.