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. 2022 May 18;12(5):e049949. doi: 10.1136/bmjopen-2021-049949

Table 3.

Univariable analysis of time to death for COVID-19 patients

Characteristic HR 95% CI P value
Age group (n=787) (Reference:<20)
 21–40 1.58 0.62 to 4.06 0.3
 41–60 3.66 1.49 to 9.03 0.005
 >60 5.61 2.24 to 14.0 <0.001
Gender (n=787) (reference: female)
 Male 1.62 1.17 to 2.24 0.004
Chronic conditions (n=787) (reference: no)
 Yes 2.62 1.92 to 3.58 <0.001
Chronic conditions existing (n=787) (reference: no)
 HIV 1.49 0.83 to 2.68 0.2
 Chronic renal disease 2.77 1.80 to 4.25 <0.001
 Asthma 1.06 0.26 to 4.26 >0.9
 Tuberculosis 1.38 0.34 to 5.58 0.6
 Diabetes (n=740) 2.02 1.44 to 2.85 <0.001
Ventilation (n=787) (reference: no)
 Yes 12.3 9.06 to 16.6 <0.001
Reason hospitalisation (n=787) (reference: other reason)
 Visited hospital 106 14.7 to 758 <0.001
Clinical symptoms (n=787) (reference: no)
 Yes 1.92 1.38 to 2.67 <0.001
Symptoms existing (n=787) (reference: no) 1.13 1.04 to 1.22 0.003
 Headache 0.33 0.18 to 0.62 <0.001
 Fatigue 0.53 0.31 to 0.90 0.020
 Myalgia or arthralgia 0.24 0.03 to 1.71 0.2
 Shortness of breath 1.97 1.34 to 2.89 <0.001
 Fever 1.92 1.39 to 2.65 <0.001
 Cough 1.25 0.93 to 1.67 0.14
 Sore throat 1.86 0.92 to 3.79 0.086
 Weakness 1.80 1.02 to 3.16 0.042
 Chest pains (n=740) 0.62 0.25 to 1.50 0.3
 Loss of taste or smell 3.43 2.52 to 4.68 <0.001
White blood cells (n=558) (reference: normal)
 Decreased 0.57 0.26 to 1.24 0.2
 Increased 3.14 2.27 to 4.34 <0.001
Neutrophils (n=559) (reference: normal)
 Decreased 3.34 1.88 to 5.95 <0.001
 Increased 6.13 3.22 to 11.7 <0.001
Lymphocytes (n=558) (reference: normal)
 Decreased 4.17 1.95 to 8.90 <0.001
 Increased 0.30 0.06 to 1.45 0.13
Haemoglobin (n=554) (reference: normal)
 Decreased 2.81 2.01 to 3.92 <0.001
 Increased 0.88 0.40 to 1.94 0.8
Alanine aminotransferase (n=500) (reference: normal)
 Increased 2.13 1.54 to 2.95 <0.001
Aspartate aminotransferase (n=502) (reference: normal)
 Increased 3.24 2.25 to 4.68 <0.001
Potassium (n=539) (reference: normal)
 Decreased 1.15 0.65 to 2.05 0.6
 Increased 1.72 1.20 to 2.46 0.003
C reactive protein (n=263) (reference: normal)
 Increased 25.9 3.61 to 186 0.001