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. Author manuscript; available in PMC: 2022 Jul 13.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jan 27;109:110255. doi: 10.1016/j.pnpbp.2021.110255

Figure 2. Cilia differentially expressed genes in SCZ, ASD, BP, and MDD.

Figure 2.

Figure 2.

a. Volcano plot showing DEGs (P <0.05). Scattered points represent cilia genes: the x axis is the fold change while the y axis is the -log p value. Green and red dots refer to upregulated and downregulated genes. Genes circled in blue represent GPCRs that localize to the cilium.

b. Histogram showing the cilia genes and non-cilia genes that are differentially expressed in SCZ; Exact Fisher test OR = 1.681, P < 0.0001.

c. Histogram showing cilia GPCR genes and non-cilia GPCR genes that are differentially expressed in SCZ; Exact Fisher test: OR: 6.873, P = 0.0001.

d-f. Volcano plots of cilia DEGs in (d) ASD, (e) BP, and (f) MDD.