System building blocks |
Governance |
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Clear definition of roles between national, regional or local levels in terms of decision-making, organization, and deployment of screening, with centralized monitoring of data and a national protocol guiding all implementation
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Opportunities for the involvement of relevant professional societies and patient organizations in decision-making on lung cancer screening
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Information |
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Comprehensive data management system, covering all aspects of the program
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Full interoperability between screening program and health data systems to capture outcomes for all screening attendees and ensure regular updating of invitation database
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Widespread information campaign conveying appropriate, accessible information about screening through all possible channels
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Health workforce |
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Comprehensive workforce planning to ensure sufficient personnel to perform scans and follow-up care
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Training and accreditation criteria are defined for all imaging personnel and applied in all participating screening centers
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Full engagement of primary care physicians, with appropriate training in place
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Medical technologies |
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Quality criteria for CT scans and low-dose specifications consistent across all screening centers
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Identification of the best software to perform a volumetric assessment of nodules
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Use of AI to aid interpretation of scans
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Service delivery |
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Screening program fully integrated into multidisciplinary care pathways
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Preemptive addressing of any deficits along the lung cancer pathway that may result in delays in diagnosis and access to care
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Full integration of lung cancer screening program with an existing smoking cessation program
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System goals |
Access, coverage, equity, and responsiveness |
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Optimal selection criteria for screening are defined, to ensure broad outreach to the population at the highest risk of lung cancer, and built into the invitation database
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The selection of organization model (centralized vs. decentralized) balances the need for consistent quality with ease of access to the population
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Shared decision-making is built into screening protocol to ensure participants are fully informed of the risks and benefits of screening
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Targeted outreach and careful messaging to address known barriers to attendance in vulnerable groups, including fears of diagnosis, and stigma surrounding smoking
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Quality and safety |
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Systematic quality assurance is built into all screening centers, regardless of location, and quality assurance metrics established from outset of the program
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A consistent definition of ‘low dose’ adopted across all screening centers
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Efficiency |
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Centralized coordination of the program, building economies of scale with other screening programs, as appropriate
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Exploration of individualized screening protocols on the basis of biomarkers or other factors to minimize false positives, unnecessary scans, and exploratory procedures (also relevant to “Quality and safety”)
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Population health |
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Monitoring of lung cancer cases detected by the program, and outside of it, stratified by socioeconomic, and demographic data
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Monitoring of impact on stage distribution and lung cancer mortality through appropriate data linkages to cancer registry
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