Table 1.
Demographic, Clinical, and Treatment Characteristics
| Characteristic | N (%) |
p Value | ||
|---|---|---|---|---|
| Total | AD | No AD | ||
| N | 48 | 16 | 32 | |
| Mean age at diagnosis (y) (SD) | 54 (15) | 51 (17) | 55 (14) | 0.37 |
| Male sex | 30 (63) | 8 (50) | 22 (69) | 0.21 |
| Race | ||||
| Black | 0 (0) | 0 (0) | 0 (0) | 0.46 |
| Native American or Alaskan Native | 1 (2.1) | 0 (0) | 1 (3.1) | |
| Asian | 22 (46) | 10 (63) | 12 (38) | |
| White | 18 (38) | 5 (31) | 13 (41) | |
| Native Hawaiian or Other Pacific Islander | 2 (4.2) | 0 | 2 (6.3) | |
| Other | 5 (10) | 1 (6.3) | 4 (13) | |
| WHO classification | ||||
| Thymoma | 28 (58) | 13 (81) | 15 (47) | 0.01 |
| Thymic carcinoma | 18 (38) | 2 (13) | 16 (50) | |
| Not defined | 2 (4) | 1 (6) | 1 (3) | |
| Masaoka-Koga stage at diagnosis | ||||
| I | 2 (4.2) | 1 (6.3) | 1 (3.2) | 0.81 |
| II | 2 (4.2) | 1 (6.3) | 1 (3.2) | |
| III | 9 (19) | 3 (19) | 6 (19) | |
| IV | 30 (63) | 8 (50) | 22 (69) | |
| Not defined | 5 (10) | 3 (19) | 2 (6.3) | |
| Total thymectomy | 29 (60) | 10 (63) | 19 (59) | 0.84 |
| Radiation therapya | 36 (75) | 11 (69) | 25 (78) | 0.48 |
| Systemic treatment for thymic neoplasm | 46 (96) | 15 (94) | 31 (97) | 0.61 |
| Median number of systemic treatments (range) | 3.0 (0–8) | 3.0 (0–5) | 3.0 (0–8) | 0.83 |
Note: Data are expressed as number and percentage, n (%) except where otherwise stated. Bold values indicate statistical significant.
AD, autoimmune disease.
a
Indications for radiation therapy included the following: adjuvant, definitive, oligometastatic, and palliative.