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. 2022 Apr 11;13:860510. doi: 10.3389/fgene.2022.860510

TABLE 5.

The performances of models on THCA and lung cancer samples.

THCA (170) a Lung (184)
MTLOG b MCAT MCNN MTLION MLLOG MCAT MCNN MLLION
ACC 0.651 0.693 0.753 0.872 0.659 0.698 0.732 0.818
SEN 0.444 0.488 0.418 0.775 0.552 0.625 0.538 0.730
SPE 0.800 0.827 0.973 0.957 0.712 0.750 0.869 0.882
AUC 0.600 0.692 0.724 0.974 0.680 0.736 0.753 0.899

ACC, accuracy; SEN, sensitivity; SPE, specificity; AUC, area under the receiver operating characteristic curve; THCA, thyroid cancer.

a

Each group of samples was a mix of cancer and control samples (n = 260).

b

The threshold of both MLOG and MLION was 0.5 for two samples and the thresholds of MCAT and MCNN were set by Youden index (MCAT: 0.336 for THCA and 0.321 for lung cancer; MCNN: 0.433 for THCA and 0.419 for lung cancer).