TABLE 5.
THCA (170) a | Lung (184) | |||||||
---|---|---|---|---|---|---|---|---|
b | MCAT | MCNN | MCAT | MCNN | ||||
ACC | 0.651 | 0.693 | 0.753 | 0.872 | 0.659 | 0.698 | 0.732 | 0.818 |
SEN | 0.444 | 0.488 | 0.418 | 0.775 | 0.552 | 0.625 | 0.538 | 0.730 |
SPE | 0.800 | 0.827 | 0.973 | 0.957 | 0.712 | 0.750 | 0.869 | 0.882 |
AUC | 0.600 | 0.692 | 0.724 | 0.974 | 0.680 | 0.736 | 0.753 | 0.899 |
ACC, accuracy; SEN, sensitivity; SPE, specificity; AUC, area under the receiver operating characteristic curve; THCA, thyroid cancer.
Each group of samples was a mix of cancer and control samples (n = 260).
The threshold of both MLOG and MLION was 0.5 for two samples and the thresholds of MCAT and MCNN were set by Youden index (MCAT: 0.336 for THCA and 0.321 for lung cancer; MCNN: 0.433 for THCA and 0.419 for lung cancer).