Table 1. Thermodynamic Data for Secondary Association of Aromatic Residue-Containing Tripeptides and Control Tripeptides with the 1:1 Complex of F′GG-CB[8]a.
| model peptide | Ka (103 M–1) | ΔHa (kcal mol–1) | –TΔSa (kcal mol–1) |
|---|---|---|---|
| WGG | 460 ± 53 | –13.3 ± 0.2 | 5.6 ± 0.2 |
| GWG | 103 ± 6 | –11.9 ± 0.1 | 5.0 ± 0.1 |
| GGW | 90 ± 7 | –14.5 ± 0.3 | 7.8 ± 0.4 |
| FGG | 356 ± 26 | –14.4 ± 0.4 | 6.8 ± 0.3 |
| GFG | 58 ± 3 | –9.1 ± 0.4 | 2.6 ± 0.4 |
| GGF | 22 ± 1 | –7.5 ± 0.2 | 1.5 ± 0.2 |
| YGG | 3 ± 5 | –9.6 ± 0.1 | 3.6 ± 0.2 |
| GYG | 4 ± 0.3 | –4.7 ± 0.2 | –0.2 ± 0.3 |
| GGY | –b | –b | –b |
| NpGG | 382 ± 22 | –14.6 ± 0.2 | 7.0 ± 0.2 |
| GNpG | 165 ± 10 | –12.7 ± 0.4 | 5.6 ± 0.4 |
| GGNp | 90 ± 2 | –12.0 ± 0.1 | 5.2 ± 0.1 |
| KGG | –b | –b | –b |
| EGG | –b | –b | –b |
| LGG | –b | –b | –b |
a
Averaged with three replicates.
b
Not detected.