. 2022 May 5;144(19):8734–8740. doi: 10.1021/jacs.2c02422

Table 2. Scope of the Asymmetric Double Hydrogenation of Enones^a.

Reaction conditions: 0.1 mmol of the substrate, 1.0 mol % catalyst, 1.0 mol % additive, 2 mL of toluene, 50 bar H₂, 16 h, rt. Product distribution was determined by ¹H NMR spectroscopy. Stereoselectivity was determined by SFC or GC analysis, using chiral stationary phases. (i) Catalyst D was used.

Table 2. Scope of the Asymmetric Double Hydrogenation of Enonesa.

Table 2. Scope of the Asymmetric Double Hydrogenation of Enones^a.