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. 2022 May 6;33(5):969–981. doi: 10.1021/acs.bioconjchem.2c00167

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© 2022 The Authors. Published by American Chemical Society

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Antiproliferative effect in BT474 and MCF7 cells produced: (A) by free doxorubicin after continuous incubation with various drug concentrations for 72 h (n = 3); (B) after 72 h of continuous incubation with aHER2-DOX-MaMAs at 0.35 μg/mL free doxorubicin equivalent concentration (n = 3); (C) after 2.5 h of total incubation with aHER2-DOX-MaMAs at 0.0875 μg/mL free doxorubicin equivalent concentration (n = 11); in panel (C) a magnet was applied only during the first 30 min of incubation with the aHER2-DOX-MaMAs.