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. 2022 May 20;48:101453. doi: 10.1016/j.eclinm.2022.101453

Table 2.

Laboratory findings and comorbidities of the hospitalized patients according to their vaccination status.

All patients (N = 1888) Unvaccinated (N = 1327) Partially vaccinated (N = 352) Fully vaccinated (N = 209) Partially vaccinated p value † Full vaccinated p value †
Comorbidities

 Any comorbidity 705 (37·5%) 434 (33%) 139 (40%) 132 (63·5%) 0·017 <0·0001
 No comorbidities 1177 (62·5%) 889 (67%) 212 (60%) 76 (36·5%) 0·017 <0·0001
 1 Comorbidity 447 (24%) 306 (23%) 84 (24%) 57 (27%) 0·75 0·18
 2 Comorbidities 157 (8%) 83 (6%) 38(11%) 36 (17%) 0·003 <0·0001
 More than 2 101 (6%) 45 (3%) 17 (5%) 39 (19%) 0·20 <0·0001

 Obesity 330 (17·5%) 229 (17%) 54 (15%) 47 (22%) 0·399 0·069
 Hypertension 289 (15%) 144 (11%) 59 (17%) 86 (41%) 0·002 <0·0001
 Pneumophathy 155 (8%) 91 (7%) 28 (8%) 36 (17%) 0·472 <0·0001
 Diabetes mellitus 186 (10%) 92 (7%) 50 (14%) 44 (21%) <0·0001 <0·0001
 Heart disease 78 (4%) 37 (3%) 14 (4%) 27 (13%) 0·246 <0·0001
 Cancer 39 (2%) 23 (2%) 6 (2%) 10 (5%) 0·972 0·009
 Chronic kidney disease 31 (2%) 13 (1%) 5 (1%) 13 (6%) 0·474 <0·0001

Laboratory findings

 Lymphocytes (units/µL) 1190·0 (850·0–1650·0) 1180·0 (840·0–1617·5) 1240·0 (900·0–1725·0) 1180·0 (850·0–1785·0) 0·046 0·622
 Platelets (units/mL) 237·0 (184·0–314·0) 233·0 (180·0–313·0) 241·0 (189·0–314·5) 253·0 (195·25–325·25) 0·298 0·038
 C-reactive protein (mg/L) 34·5 (15·0–75·6) 31·8 (14·1–68·7) 37·05 (16·2·0–81·5) 48·9 (21·7–102·9) 0·017 <0·0001
 Lactate dehydrog. (units/L) 304·0 (248·0–374·0) 313·0 (258·0–386·0) 282·0 (232·0–352·5) 269·0 (218·5–330·5) <0·0001 <0·0001
 Ferritin (ng/mL) 490·0 (222·0–1028·7) 527·0 (237·2–1083·5) 433·0 (195·0–932·0) 367·0 (182·0–731·0) 0·010 <0·0001
 D-dimer (ug/mL) 400·0 (280·0–605·0) 410·0 (280·0–600·0) 370·0 (270·0–560·0) 410·0 (270·0–695·0) 0·053 0·659
 Procalcitonin (ng/mL) 0·09 (0·05–0·17) 0·08 (0·05–0·16) 0·09 (0·06–0·16) 0·11 (0·06–0·35) 0·572 0·135

Data are the median (IQR) or the number of cases (n) and percentage (%) calculated as [n/N]*100, where N is the total number of patients in the corresponding group. †, p values were calculated by comparing the unvaccinated group and the corresponding vaccinated group (partially or fully vaccinated patients) with the χ2 test, Fisher`s exact test or Mann-Whitney U test. Lactate dehydrog., lactate dehydrogenase.