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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Nat Chem. 2021 Nov 25;14(1):85–93. doi: 10.1038/s41557-021-00826-8

Table 1.

Blood PK half-lives of CBPs in healthy balb/c mice.

Distribution (α)
Phase t1/2 (h)
Clearance (β)
Phase t1/2 (h)
R2 of
Fit
5A-R-Cy 0.14 1.26 0.9196
5A-S-Cy 0.80 5.28 0.9999
2A-R-Cy 1.73 10.70 0.9948
2A-S-Cy 1.54 8.57 0.9957