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. 2022 Mar 23;64(Suppl 2):S484–S498. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_22_22

Table 14.

Medications used in managing agitation

Initial dose (mg) Tmax* (min) Can repeat (h) Maximum dose (per 24 h), mg
Oral
 Risperidone 2 1 h 2 6
 Olanzapine 5-10 6 h 2 20
 Haloperidol 5 30-60 15 m 20
 Lorazepam 2 20-30 2 12
IM
 Olanzapine 10 15-45 20 m 30
 Haloperidol 5 30-60 15 m 20
 Lorazepam 2 20-30 2 12
 Ziprasidone 10-20 15 10 mg q 2 h 40
20 mg q 4 h
 >Aripiprazole 9.75 1 h 2 30
IV
 Haloperidol 5 Immediate 4 10
 Lorazepam 2 Immediate 2 12

Maximum doses can vary depending on the outcome. q 2 h – Every 2 hours; q 4 h – Every 4 hours, IM – Intramuscular; IV – Intravenous