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. 2022 May 20;19(8):533–550. doi: 10.1038/s41575-022-00608-8

Fig. 1. Major breakthroughs in HCV history.

Fig. 1

Breakthroughs are separated into basic and translational (part a) and clinical (part b) research, and research that formed part of major awards is indicated. DAA, direct-acting antiviral agent; HCV, hepatitis C virus; IFN, interferon-α; NANBH, non-A, non-B hepatitis; NS5A, nonstructural protein 5A; Peg-IFN, pegylated interferon-α; PI, protease inhibitor; RBV, ribavirin; SOF, sofosbuvir; SVR, sustained virological response; VEL, velpatasvir; VOX, voxilaprevir. Additional refs263,264.