TABLE 6.
Change from baseline of mean FACE-Q scores used in “other” treatment studies.
| ARTICLE | Hassan, 2020 JCD36 | Nacopoulos, 2019, JCD37 | Lee 2019, JCD38 | Tenna, 2017 Aesth Plast Surg39 | Santorelli, 2021 JCD40 | Nestor, 2019 JCAD41 | Samizadeh, 2020 JCD42 | |
| PRODUCT | PRF x 3 treatments | PRF x 3 treatments | PRP x 1 treatment | Nanofat/PRP + CO2 Laser | Threading (Definisse™ free floating threads) | Threading-absorbable suspension sutures (82% poly-L -lactic Acid & 18% glycolide polymer) | Microneedling + Topical GF Serum | |
| TREATMENT SITE | Malar area, NLF, Upper lip | Full Face | Midface | B/L cheeks | Midface | Midface | Full Face | |
| INJECTION TECHNIQUE | NR | NR | Intradermal Injections | Serial puncture | NA | NA | Microneedling | |
| VOLUME USED (MEAN) | 1 cc in each area | NR | 4 mL | 3 mL PRP + 7mL Nanofat | 4 threads (2 B/l) | – | 2 mL GF serum | |
| FOLLOW UP | 3 months s/p initial treatment |
3 months s/p initial treatment |
6 weeks s/p single treatment |
1 year s/p 2 treatments |
10 months s/p initial treatment |
12 weeks s/p initial treatment |
6 weeks s/p initial treatment |
|
| CHANGE FROM BASELINE OF MEAN FACE-Q SCORE | SATISFACTION WITH FACIAL APPEARANCE | 17.9* | NR | NR | Mean Raschtransformed FACE-Q, Score NR | 15.18 | 37 | NR |
| SATISFACTION WITH SKIN | 22.6* | 3 | NR | NR | NR | NR | Mean Raschtransformed FACE-Q, Score NR | |
| SATISFACTION WITH CHEEKS | 31.7* | NR | NR | NR | NR | 37 | NR | |
| SATISFACTION WITH LOWER FACE AND JAWLINE | 35.7* | NR | NR | NR | NR | NR | NR | |
| SATISFACTION WITH LIPS | 18.3* | NR | NR | NR | NR | NR | NR | |
| SATISFACTION WITH OUTCOME | NR | NR | 74.2% | NR | NR | NR | 72% | |
| AGE APPRAISAL VAS | NR | NR | 1.6 years younger | NR | NR | 3.4 years younger | NR | |
*Significant (p<0.05) compared to baseline. B/L: Bilateral; GF: Growth Factor; NLF: Nasolabial fold; NA: Not applicable; NR: Not reported; PRF: Platelet rich fibrin; PRP: Platelet rich plasma