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. 2022 May 20;8(20):eabk2746. doi: 10.1126/sciadv.abk2746

Fig. 8. AXL mRNA biological changes after dual HER2 blockade.

Fig. 8.

AXL mRNA expression changes between baseline and day 14 of treatment in all 139 tumor samples from PAMELA clinical trial (A) and across histological subtypes (B) and PAM50 subtypes (C). (D) AXL mRNA expression changes between baseline, day 14, and surgery in 97 residual tumors at surgery. (E) Correlation between AXL, VIM, and ERBB2 in 96 tumor samples from the PAMELA clinical trial. Each line represents a tumor sample. Increases are represented in orange, and decreases in blue. P values were determined by two-tailed paired t tests.