Figure 6.
Histological staining of (A) UN-1 and (B) UN-2. (C) Light microscopic image representing the distribution of methylene blue after puncturing of the skin with self-dissolving microneedle. The image also represents the successful piercing of skin (C1) immediately after microneedle insertion, and skin resealing (C2) after 2 hours, and (C3) after 12 hours.