Table 3.
Performance evaluation of gene differential expression in 10 imputation methods
| Methods | Down expression | NotSig expression | Up expression | Differential expression |
|---|---|---|---|---|
| Bulk | 5776 | 5355 | 5252 | 11028 |
| Raw | 5956 | 7358 | 3069 | 9025 |
| scImpute | 8231 | 3948 | 4204 | 12435 |
| SAVER | 3038 | 9323 | 4022 | 7060 |
| MAGIC | 5389 | 6161 | 4833 | 10222 |
| ALRA | 5965 | 4346 | 6072 | 12037 |
| DrImpute | 8868 | 3846 | 3890 | 12758 |
| DeepImpute | 7830 | 5322 | 3231 | 11061 |
| scTSSR | 7763 | 4050 | 1898 | 9661 |
| scNPF | 2265 | 10211 | 3907 | 6172 |
| scIGANs | 912 | 12528 | 2943 | 3855 |
| scGNN | 503 | 928 | 569 | 1072 |