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Canine DUXC locus makes two different isoforms. (A) Top panel shows a schematic of the exons encoding DUXC and DUXC-ALT and the bottom panel shows the alignment in the first homeodomain region with mouse Dux and Human DUX4 HD1. (B) Nested PCR primers specific to the DUXC (top panel) or DUXC-ALT (middle panel) mRNA isoforms show DUXC expression in testis a variably in hippocampus; DUXC-ALT is identified in testis, thymus and hippocampus.
