Table 4.
Results from multivariable logistic regression models for Q1–Q6, Q18–Q19
| Question | Outcome | Covariate | Level | OR | 95% CI | p value |
|---|---|---|---|---|---|---|
| Q1: Your health information is divided into several different sections (e.g. diagnoses test results and images such as x-rays or scans). Would you like to: | 1 = share all information; 0 = share some information | Cohort | Pandemic versus pre-pandemic | 1.71 | (0.87, 3.36) | 0.12 |
| Age group | 50–74 versus 75+ | 1.26 | (0.51, 3.10) | 0.61 | ||
| Age group | < 49 versus 75+ | 0.92 | (0.30, 2.76) | 0.88 | ||
| Sex | Female versus male | 0.27 | (0.13, 0.56) | 0.0004 | ||
| Treatment phase | Follow-up versus treatment | 1.25 | (0.64, 2.43) | 0.52 | ||
| Treatment phase | Pre-treatment versus treatment | 2.1 | (0.44, 9.97) | 0.35 | ||
| Education | Post-sec. versus no/incomplete post-sec | 0.84 | (0.40, 1.79) | 0.66 | ||
| Q2: Your biological samples are classified into several different types (e.g. blood urine tissues). Would you like to: | 1 = share all information; 0 = share some information | Cohort | Pandemic versus pre-pandemic | 2.11 | (1.03, 4.34) | 0.042 |
| Age group | 50–74 versus 75+ | 1.33 | (0.51, 3.46) | 0.56 | ||
| Age group | < 49 versus 75+ | 1.09 | (0.34, 3.49) | 0.89 | ||
| Sex | Female versus male | 0.28 | (0.13, 0.60) | 0.0011 | ||
| Treatment phase | Follow-up versus treatment | 1.27 | (0.63, 2.54) | 0.50 | ||
| Treatment phase | Pre-treatment versus treatment | 3.97 | (0.49, 32.12) | 0.20 | ||
| Education | Post-sec. versus no/incomplete post-sec | 0.55 | (0.23, 1.30) | 0.17 | ||
| Q3: There are many different areas of medical research (e.g. research on cancer diabetes reproductive disorders genetic disorders heart disease etc.). Would you like to: | 1 = share all information; 0 = share some information | Cohort | Pandemic versus pre-pandemic | 1.84 | (0.97, 3.48) | 0.062 |
| Age group | 50–74 versus 75+ | 0.69 | (0.26, 1.81) | 0.45 | ||
| Age group | < 49 versus 75+ | 0.57 | (0.18, 1.77) | 0.33 | ||
| Sex | Female versus male | 0.22 | (0.11, 0.44) | < .0001 | ||
| Treatment phase | Follow-up versus treatment | 0.98 | (0.53, 1.83) | 0.95 | ||
| Treatment phase | Pre-treatment versus treatment | 2.07 | (0.44, 9.79) | 0.36 | ||
| Education | Post-sec. versus no/incomplete post-sec | 0.7 | (0.33, 1.46) | 0.34 | ||
| Q4: When asked for consent to share your information or samples would you like to have an option to think about the decision and be asked again later? | 1 = option to re-consider; 0 = no option to re-consider | Cohort | Pandemic versus pre-pandemic | 0.85 | (0.56, 1.28) | 0.43 |
| Age group | 50–74 versus 75+ | 1.64 | (0.94, 2.87) | 0.083 | ||
| Age group | < 49 versus 75+ | 2.28 | (1.08, 4.81) | 0.0307 | ||
| Sex | Female versus male | 1.05 | (0.69, 1.58) | 0.83 | ||
| Treatment phase | Follow-up versus treatment | 1.16 | (0.76, 1.78) | 0.48 | ||
| Treatment phase | Pre-treatment versus treatment | 1.32 | (0.60, 2.92) | 0.49 | ||
| Education | Post-Sec. versus no/incomplete post-sec | 0.87 | (0.55, 1.36) | 0.53 | ||
| Q5: Your health information and samples are often requested for future studies. Would you like to: | 1 = broad consent; 0 = study-specific consent | Cohort | Pandemic versus pre-pandemic | 0.78 | (0.50, 1.21) | 0.27 |
| Age group | 50–74 versus 75+ | 0.61 | (0.34, 1.12) | 0.11 | ||
| Age group | < 49 versus 75+ | 0.43 | (0.20, 0.95) | 0.0366 | ||
| Sex | Female versus male | 0.55 | (0.36, 0.85) | 0.0068 | ||
| Treatment phase | Follow-up versus treatment | 0.84 | (0.54, 1.31) | 0.45 | ||
| Treatment phase | Pre-treatment versus treatment | 1.19 | (0.49, 2.90) | 0.70 | ||
| Education | Post-sec. versus no/incomplete post-sec | 1.18 | (0.73, 1.90) | 0.51 | ||
| Q6: A contact pool may be created with patient names phone numbers and key pieces of health information. UHN Researchers with ethical approval for their studies could search this pool to find participants. Would you prefer to be: | 1 = automatically entered into a contact pool; 0 = asked for permission | Cohort | Pandemic versus pre-pandemic | 1.12 | (0.73, 1.72) | 0.60 |
| Age group | 50–74 versus 75+ | 0.75 | (0.42, 1.32) | 0.32 | ||
| Age group | < 49 versus 75+ | 0.59 | (0.27, 1.27) | 0.18 | ||
| Sex | Female versus male | 0.74 | (0.49, 1.14) | 0.17 | ||
| Treatment phase | Follow-up versus treatment | 0.84 | (0.55, 1.31) | 0.45 | ||
| Treatment phase | Pre-treatment versus treatment | 0.97 | (0.42, 2.26) | 0.95 | ||
| Education | Post-sec. versus no/incomplete post-sec | 1.76 | (1.09, 2.85) | 0.0204 | ||
| Q18: Would you like to be able to track who is using your information or samples and what they are using it for? | 1 = wanting to track information/sample use; 0 = not wanting to track information/sample use | Cohort | Pandemic versus pre-pandemic | 1.89 | (1.18, 3.03) | 0.0079 |
| Age group | 50–74 versus 75+ | 1.98 | (1.12, 3.51) | 0.0185 | ||
| Age group | < 49 versus 75+ | 2.68 | (1.15, 6.26) | 0.0223 | ||
| Sex | Female versus male | 1.12 | (0.71, 1.78) | 0.61 | ||
| Treatment phase | Follow-up versus treatment | 1.61 | (1.00, 2.61) | 0.0498 | ||
| Treatment phase | Pre-treatment versus treatment | 1.3 | (0.54, 3.13) | 0.55 | ||
| Education | Post-sec. versus no/incomplete post-sec | 1.18 | (0.72, 1.94) | 0.50 | ||
| Q19: Would you like to be notified with the results of studies that have used your information or samples? | 1 = wanting to be notified of study results; 0 = not wanting to be notified of study results | Cohort | Pandemic versus pre-pandemic | 2.06 | (1.21, 3.51) | 0.0082 |
| Age group | 50–74 versus 75+ | 1.56 | (0.84, 2.88) | 0.16 | ||
| Age group | < 49 versus 75+ | 2.67 | (0.99, 7.22) | 0.053 | ||
| Sex | Female versus male | 1.16 | (0.70, 1.94) | 0.56 | ||
| Treatment phase | Follow-up versus treatment | 1.59 | (0.93, 2.72) | 0.092 | ||
| Treatment phase | Pre-treatment versus treatment | 0.84 | (0.34, 2.08) | 0.70 | ||
| Education | Post-sec. versus no/incomplete post-sec | 1.02 | (0.59, 1.76) | 0.95 |
The outcome column outlines how the outcome was coded for each question