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. 2022 May 21;49(10):9915–9927. doi: 10.1007/s11033-022-07539-2

Fig. 1.

Fig. 1

The gene for KNG is present on q-arm of chromosome 3. Boxes 1–11 show the respective exons with intermittent introns. KNG gene undergoes alternative splicing to form HMWK and LMWK. Boxes 1–9 codes for signal peptide and heavy chain of HMWK and LMWK. Exon 10b encodes the bradykinin sequence. Exon 10b codes for the light chain of HMWK, whereas exon 11 contains sequences characteristic of the LMWK light chain