Skip to main content
. 2022 Apr 25;15:495–503. doi: 10.1016/j.bioactmat.2022.04.014

Table 4.

The research question defined as PICOS for the listed clinical study [38].

PICOS Definition
Population Adults (18–90 years' old)
Intervention Composite inlays or onlays
Control Ceramic inlays or onlays
Outcome Clinical performance of the dental restorations (USPHS criteria, CDA criteria, FDI criteria et al.); Failure
Study designs Randomized clinical studies or trials comparing at least two esthetic materials for inlay/onlay manufacturing (at least one ceramic and at least one composite)