Table 5.
Detergents used for membrane solubilisation, including their abbreviations as used in the following, as well as suppliers.
| Detergent | Critical micelle concentration in water (CMC) (mM) | Micelle MW (kDa) |
|---|---|---|
| n-Dodecyl β-D-maltoside (DDM, Thermo Fisher Scientific) | 0.17; 0.12 (with 0.2 M NaCl)a,b | ~ 72b |
| n-Decyl-β-D-maltoside (DM, Cube Biotech) | 1.66a | ~ 33 (69 molecules)b |
| 3-((3-Cholamidopropyl) dimethylammonio)-1-propanesulfonate (CHAPS, Sigma-Aldrich) | 4.2–6.3a | ~ 6.2c |
| Fos-choline-12 (FC-12, Cube Biotech) | 1.5a | ~ 19 (54 molecules)b |
| Dodecyldimethylaminoxid (LDAO, Sigma Aldrich) | 1–2b | ~ 17–22b |
| Octylthioglucoside (OTG, Cube Biotech) | 9 mMa | Unknown |
References of the CMC-values and the micelle MW.
acube-biotech.com.