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. 2022 May 20;13:2819. doi: 10.1038/s41467-022-30513-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A Pearson correlation coefficients for both mRNA/flux and protein/flux pairs, with the distribution of Pearson correlation coefficients for protein/flux pairs shown on the right margin and for mRNA/flux pairs shown on the top margin. B Pathway enrichment analysis for both significantly positively correlated and negatively correlated reactions. Figures above each bar are adjusted p values. C Overview of EMP pathway reactions with changes in absolute reaction fluxes, protein phosphorylation levels, absolute protein abundance and absolute mRNA abundance. The abscissas for all bar plots are specific growth rates of yeast cells. Details of the bar plots included in this panel can be found in the Supplementary Information. Source data are provided as a Source Data file.