Fig. 4. Analytical precision and reproducibility of elio tissue complete eTMB.

Precision and reproducibility of elio-predicted exome tumor mutation burden (eTMB) measured in mutations per megabase (muts/Mb) across three independent clinical laboratories using 21 FFPE tumor and cell-line samples. At each site, each sample was analyzed by two operators on two sequencing instruments across three non-consecutive days as indicated. The coefficient of variation (CV) and standard deviation (SD) for each sample are indicated, demonstrating high performance of eTMB across standard clinical laboratory variables. Source data are provided as a Source Data file.