Fig. 6. Analytical precision and reproducibility of the elio tissue complete MSI detection algorithm.

Precision and reproducibility of the microsatellite instability (MSI) status from elio tissue complete were evaluated across three independent clinical laboratories using 21 FFPE and cell-line samples. At each site, each sample was analyzed by two operators on two sequencing instruments across three non-consecutive days as indicated. The absolute value of the coefficient of variation (CV) and standard deviation (SD) for each sample are indicated. Samples with a combined score above the dotted line are considered microsatellite instability-high, demonstrating high performance of MSI across standard clinical laboratory variables. Source data are provided as a Source Data file.