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. 2022 May 20;12:8580. doi: 10.1038/s41598-022-12206-4

Table 1.

Food intake, anthropometry, and metabolic parameters from an in vivo study.

Parameters Week 4 Week 8
NDV NDD HFV HFDD NDV NDD HFV HFDD
Food intake (g/day) 23.55 ± 1.1 22.98 ± 1.3 24.38 ± 0.8 23.42 ± 0.9 24.46 ± 1.1 23.74 ± 1.2 23.88 ± 0.8 24.53 ± 1.0
Body weight (g) 460 ± 11.5 472.7 ± 13.3 635.8 ± 6.5* 638.9 ± 9.6* 473.6 ± 8.4 479.7 ± 7.6 645.3 ± 8.7* 655.7 ± 15.2*
Visceral fat weight (g) 19.75 ± 1.5 23.58 ± 1.1 47.26 ± 4.9* 54.84 ± 4.2* 22.86 ± 1.1 23.91 ± 1.2 54.98 ± 1.8* 60.87 ± 2.5*
Plasma glucose (mg/dL) 130.4 ± 4.7 128.9 ± 6.1 127.9 ± 5.08 129.7 ± 4.6 144.2 ± 9.1 141.9 ± 10.8 147.5 ± 12.4 145.8 ± 9.8
Plasma insulin (ng/ml) 4.26 ± 0.6 9.856 ± 1.9* 8.956 ± 0.9* 12.01 ± 1.4* 4.459 ± 0.9 11.34 ± 3.05* 10.57 ± 2.2* 12.84 ± 2.2*
AUC of glucose (mg/dl × min × 104) 2.34 ± 0.1 3.16 ± 0.1* 3.06 ± 0.3* 2.98 ± 0.8* 2.11 ± 0.2 3.07 ± 0.2* 3.09 ± 0.3* 2.77 ± 0.1*
HOMA-IR 19.28 ± 2.0 56.98 ± 4.2* 71.93 ± 4.1* 74.84 ± 9.2* 20.49 ± 2.2 97.17 ± 11.4* 93.20 ± 9.9* 79.13 ± 14.2*
Triglycerides (mg/dL) 89.87 ± 5.4 89.59 ± 2.9 87.04 ± 7.2 99.58 ± 1.6 86.82 ± 5.6 89.06 ± 3.1 84.42 ± 4.8 84.11 ± 3.8
Total cholesterol (mg/dL) 81.19 ± 4.0 84.11 ± 2.7 109.5 ± 14.9* 105.7 ± 5.2* 78.77 ± 5.7 80.35 ± 2.6 122.8 ± 4.9* 112.1 ± 3.9*
HDL cholesterol (mg/dL) 34.45 ± 1.3 32.7 ± 1.0 24.33 ± 1.0* 24.72 ± 1.6* 35.31 ± 0.9 33.32 ± 1.5 25.27 ± 2.5* 24.0 ± 3.5*
LDL cholesterol (mg/dL) 23.69 ± 3.5 25.77 ± 3.1 44.11 ± 5.0* 42.32 ± 4.0* 25.73 ± 2.1 26.59 ± 2.2 44.90 ± 4.4* 48.13 ± 1.6*

Data are reported as mean ± SEM (n = 6/group).

*p < 0.05 versus NDV at the same time point.

p < 0.05 versus NDD at the same time point.

p < 0.05 versus HFV at the same time point.

#p < 0.05 versus same group at the different time point.