Table 1.
Parameters | Week 4 | Week 8 | ||||||
---|---|---|---|---|---|---|---|---|
NDV | NDD | HFV | HFDD | NDV | NDD | HFV | HFDD | |
Food intake (g/day) | 23.55 ± 1.1 | 22.98 ± 1.3 | 24.38 ± 0.8 | 23.42 ± 0.9 | 24.46 ± 1.1 | 23.74 ± 1.2 | 23.88 ± 0.8 | 24.53 ± 1.0 |
Body weight (g) | 460 ± 11.5 | 472.7 ± 13.3 | 635.8 ± 6.5*† | 638.9 ± 9.6*† | 473.6 ± 8.4 | 479.7 ± 7.6 | 645.3 ± 8.7*† | 655.7 ± 15.2*† |
Visceral fat weight (g) | 19.75 ± 1.5 | 23.58 ± 1.1 | 47.26 ± 4.9*† | 54.84 ± 4.2*† | 22.86 ± 1.1 | 23.91 ± 1.2 | 54.98 ± 1.8*† | 60.87 ± 2.5*† |
Plasma glucose (mg/dL) | 130.4 ± 4.7 | 128.9 ± 6.1 | 127.9 ± 5.08 | 129.7 ± 4.6 | 144.2 ± 9.1 | 141.9 ± 10.8 | 147.5 ± 12.4 | 145.8 ± 9.8 |
Plasma insulin (ng/ml) | 4.26 ± 0.6 | 9.856 ± 1.9* | 8.956 ± 0.9* | 12.01 ± 1.4* | 4.459 ± 0.9 | 11.34 ± 3.05* | 10.57 ± 2.2* | 12.84 ± 2.2* |
AUC of glucose (mg/dl × min × 104) | 2.34 ± 0.1 | 3.16 ± 0.1* | 3.06 ± 0.3* | 2.98 ± 0.8* | 2.11 ± 0.2 | 3.07 ± 0.2* | 3.09 ± 0.3* | 2.77 ± 0.1* |
HOMA-IR | 19.28 ± 2.0 | 56.98 ± 4.2* | 71.93 ± 4.1* | 74.84 ± 9.2* | 20.49 ± 2.2 | 97.17 ± 11.4* | 93.20 ± 9.9* | 79.13 ± 14.2* |
Triglycerides (mg/dL) | 89.87 ± 5.4 | 89.59 ± 2.9 | 87.04 ± 7.2 | 99.58 ± 1.6 | 86.82 ± 5.6 | 89.06 ± 3.1 | 84.42 ± 4.8 | 84.11 ± 3.8 |
Total cholesterol (mg/dL) | 81.19 ± 4.0 | 84.11 ± 2.7 | 109.5 ± 14.9*† | 105.7 ± 5.2*† | 78.77 ± 5.7 | 80.35 ± 2.6 | 122.8 ± 4.9*† | 112.1 ± 3.9*† |
HDL cholesterol (mg/dL) | 34.45 ± 1.3 | 32.7 ± 1.0 | 24.33 ± 1.0*† | 24.72 ± 1.6*† | 35.31 ± 0.9 | 33.32 ± 1.5 | 25.27 ± 2.5*† | 24.0 ± 3.5*† |
LDL cholesterol (mg/dL) | 23.69 ± 3.5 | 25.77 ± 3.1 | 44.11 ± 5.0*† | 42.32 ± 4.0*† | 25.73 ± 2.1 | 26.59 ± 2.2 | 44.90 ± 4.4*† | 48.13 ± 1.6*† |
Data are reported as mean ± SEM (n = 6/group).
*p < 0.05 versus NDV at the same time point.
†p < 0.05 versus NDD at the same time point.
‡p < 0.05 versus HFV at the same time point.
#p < 0.05 versus same group at the different time point.