Fig. 1.

Relative risks of serious infection associated with MS disease course and disability by attained age.

Hazard ratios comparing rates of serious infections in MS patient groups by disease course and disability with rates in matched individuals from the general population without MS (= reference). All hazard ratios are derived from flexible parametric models with attained age as underlying time scale and are adjusted for matching factors (age, sex and region of residence) and educational attainment and calendar period of cohort entry.AbbreviationsMS = multiple sclerosis; EDSS = Expanded Disability Status Scale; HR = hazard ratio; CI = confidence interval.