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. 2022 Apr 16;65(2):111–125. doi: 10.33160/yam.2022.05.001

Fig. 7.

Fig. 7.

 Effects of SPMs on signaling pathways after stimulation of MH7A cells with TNF-α. MH7A cells were pretreated with SPMs for 1 h and then stimulated with 10 ng/mL TNF-α for 15 min. The effects of RvE1 on the following substances were examined: extracellular signal-regulated kinase (ERK) (A), p38 (B), c-Jun N-terminal kinase (JNK) (C), and transcription factor nuclear factor-κB (NF-κB) (D) or RvD1 on ERK (E), p38 (F), JNK (G), NF-kB (H), and maresin-1 (MaR1) on ERK (I), p38 (J), JNK (K), and transcription factor nuclear factor-κB (NF-κB) (L). The plots represent three independent experiments (*P < 0.05 vs. untreated).