Table 5.
Kruskal-Wallis test showing all 18 metabolites with statistically different (P < 0.05) abundances in the plasma of patients for each experimental group
| Metabolites | P-value | FDR |
|---|---|---|
| Amino acids | ||
| L-isoleucine | 0.000599 | 0.001433 |
| L-valine | 0.000121 | 0.000399 |
| L-pyroglutamic acid | 0.000238 | 0.000640 |
| L-Glutamine | 0.008507 | 0.015904 |
| L-asparagine | 0.010485 | 0.188850 |
| L-tyrosine | 0.014210 | 0.872890 |
| Fatty acids | ||
| Alpha-linolenic acid | 0.000068 | 0.029296 |
| Arachidonic acid | 0.000213 | 0.000636 |
| Alpha-tocopherol | 0.000222 | 0.000636 |
| Palmitic acid | 0.002714 | 0.005835 |
| Stearic acid | 0.004203 | 0.008214 |
| Carbohydrates | ||
| Myo-inositol | 0.000110 | 0.0003945 |
| D-ribose | 0.000454 | 0.001148 |
| D-threitol | 0.013159 | 0.023576 |
| D-mannose | 0.021572 | 0.231890 |
| Organic acids, nucleotides, and other classes | ||
| Uric acid | 0.003361 | 0.006882 |
| Hydrogen phosphate | 0.000814 | 0.001842 |
| Kynurenic acid | 0.013175 | 0.188850 |
Metabolites are grouped according to biochemical class. In bold, metabolites with significant FDR are shown. In total, we found 14 metabolites with both statistically significant P-value and FDR.
Abbreviation: FDR, false discovery rate.