Table 1.
Baseline clinical demographics and laboratory investigation of ICM vs. NICM
| ICM N=361 (81.67%) | NICM N=81 (18.33%) | Total N=442 | P-value | |
|---|---|---|---|---|
| Age (mean ± SD) | 68.23±10.97 | 64.09±12.22 | 67.47±11.31 | 0.003 |
| Male, n (%) | 278 (77.01%) | 52 (64.20%) | 330 (74.66%) | 0.017 |
| Nationality | ||||
| Saudi, n (%) | 270 (75.00%) | 70 (86.42%) | 340 (77.10%) | 0.027 |
| Non-Saudi, n (%) | 90 (25.00%) | 11 (13.58%) | 101 (22.90%) | |
| BMI kg/m2, mean (SD) | 28.19±5.90 | 30.83±7.28 | 28.68±6.26 | <0.001 |
| SBP mmHg median (IQR) | 119.9±21.51 | 122.1±22.35 | 120.4±21.66 | 0.415 |
| DBP mmHg median (IQR) | 67.80±12.38 | 69.23±13.59 | 68.07±12.61 | 0.356 |
| Resting HR B/min median (IQR) | 78.13±14.12 | 77.56±16.12 | 78.03±14.50 | 0.751 |
| JVP | ||||
| Normal n (%) | 179 (66.30%) | 27 (52.94%) | 206 (64.17%) | 0.068 |
| Raised n (%) | 91 (33.70%) | 24 (47.06%) | 115 (35.83%) | |
| NYHA CLASS | ||||
| I n (%) | 92 (31.51%) | 14 (24.14%) | 106 (30.29%) | 0.535 |
| II n (%) | 134 (45.89%) | 29 (50.00%) | 163 (46.57%) | |
| III n (%) | 50 (17.12%) | 13 (22.41%) | 63 (18.00%) | |
| IV n (%) | 16 (5.48%) | 2 (3.45%) | 18 (5.14%) | |
| EF% mean (SD) | 29.19±8.68 | 28.00±7.91 | 28.98±8.55 | 0.259 |
| HTN n (%) | 308 (93.05%) | 70 (86.42%) | 378 (91.75%) | 0.052 |
| Dyslipidaemia n (%) | 93 (31.85%) | 19 (23.75%) | 112 (30.11%) | 0.162 |
| Smoking n (%) | 90 (27.86%) | 7 (8.75%) | 97 (24.07%) | <0.001 |
| Atrial fibrillation history n (%) | 66 (19.02%) | 25 (31.25%) | 91 (21.31%) | 0.016 |
| H/O MI | 228 (63%) | 0 (0%) | 228 (63%) | 0.001 |
| H/O PCI | 120 (33%) | 0 (0%) | 120 (33%) | 0.001 |
| H/O CABG | 100 (28.6%) | 0 (0%) | 100 (28.6%) | 0.001 |
| ICD/CRTD n (%) | 77 (22.32%) | 28 (34.57%) | 105 (24.65%) | 0.021 |
| Anaemia n (%) | 84 (23.27%) | 23 (28.40%) | 107 (24.21%) | 0.330 |
| CKD n (%) | 190 (52.63%) | 37 (45.68%) | 227 (51.36%) | 0.258 |
| eGFR ml/minmedian (IQR) | 49.98±30.61 | 52.50±32.15 | 50.44±30.87 | 0.509 |
| Obesity n (%) | 199 (56.53%) | 53 (65.43%) | 252 (58.20%) | 0.143 |
| Thyroid disease n (%) | 37 (10.69%) | 10 (12.35%) | 47 (11.01%) | 0.669 |
| ECG | ||||
| None from those 4 findings n (%) | 171 (58.97%) | 19 (26.03%) | 190 (52.34%) | <0.001 |
| LVH n (%) | 22 (7.59%) | 8 (10.96%) | 30 (8.26%) | |
| LBBB n (%) | 31 (10.69%) | 14 (19.18%) | 45 (12.40%) | |
| Paced n (%) | 29 (10.00%) | 14 (19.18%) | 43 (11.85%) | |
| AF in ECG n (%) | 37 (12.76%) | 18 (24.66%) | 55 (15.15%) | |
| HgB gm/dl, median (IQR) | 119.5±20.56 | 117.1±20.15 | 119.1±20.48 | 0.324 |
| Serum Cr μmol /L median (IQR) | 168.5±106.8 | 170.1±129.4 | 168.8±111.2 | 0.904 |
| K, mmol/L median (IQR) | 4.41±0.61 | 4.26±0.63 | 4.38±0.62 | 0.054 |
| Iron, µmol/L median (IQR) | 9.28±5.38 | 9.97±5.76 | 9.40±5.44 | 0.406 |
| Ferritin, mcg/L median (IQR) | 202.4±218.5 | 259.6±659.8 | 212.4±338.0 | 0.278 |
| HbA1C% median (IQR) | 8.58±2.05 | 8.11±2.13 | 8.50±2.06 | 0.094 |
| NT pro BNP pg/mL, median (IQR) | 7214±8238 | 6850±8128 | 7149±8210 | 0.728 |
Values are the number of patients (%), unless indicated otherwise. BMI: Body mass index; HTN: hypertension; HR: Heart Rate; SBP: systolic blood pressure; NT-proBNP: N-terminal Pro B-type natriuretic peptide; EF: ejection fraction; ICD: implantable cardioverter defibrillator; CRT: cardiac resynchronization therapy; NYHA: New York heart association; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; bpm: beats per minute; LV: left ventricular; IQR: interquartile range; AF: atrial fibrillation; GFR: glomerular filtration rate.