Table 1.
Description of cognitive tests results at baseline and follow-up (paired Wilcoxon test, median values and IQR).
| Test | Baseline (IQR) | Follow-up (IQR) | P-value |
|---|---|---|---|
| Global tests | |||
| MMSE | 18 (15–22) | 27 (27–29) | 0.002* |
| FAB | 14 (14–17) | 17 (17–18) | 0.002* |
| Oral naming test | 39 (36–39) | 40 (37–40) | 0.03* |
| Dubois five words test | 9 (6–10) | 10 (9–10) | 0.03* |
| Executive functions | |||
| Forward digit span test | 5 | 5 | 0.30 |
| Backward digit span test | 2 | 4 | 0.005 |
| Categorical fluency test | 19 (13–23) | 29 (22–31) | 0.006 |
| Lexical fluency test | 11 (6–13) | 19 (13–22) | 0.005 |
| Similarities | 9 | 10 | 0.04 |
| Brixton | 15 | 15 | 0.27 |
| Stroop | 1 | 0 | 0.62 |
| Depression | |||
| MADRS | 14 (3·5–23) | 4 (2–10) | 0.55* |
IQR: interquartile range.
*
For these 5 tests, the threshold p-value taking into account multiplicity of tests (Bonferroni method) is 0.01. Bold font: significant results.