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. 2022 Apr 15;14(2):90–113.

Figure 6.

Figure 6

Exosome production by SMMC7721 liver cancer cells was decreased by I-ATXP treatment. Cells were treated with 0.125 mg/ml, 0.25 mg/ml, 0.5 mg/ml, and 1 mg/ml of ATX for 24 hours. (A) Expression of exosome proteins by Western blot analysis; (B) densitometry analysis showing the relative intensity of bands of Alix; and (C) densitometry analysis showing the relative intensity of bands of CD63. Data represent the mean ± SD of three independent experiments. Significant differences relative to treatment with peptide are indicated as follows: **P < 0.001, ***P < 0.0001 and ****P < 0.00001.