Table 1.
Cytotoxicity of I-ATXP (IC50, mg/ml) in different liver cancer cells
| Time | HepG2 | SMMC7721 | HKCI-C3 | MIHA |
|---|---|---|---|---|
| 24 h | 2.189±0.472* | 2.519±1.101* | 1.827±0.326** | 5.079±0.317 |
| 48 h | 0.751±0.011* | 0.941±0.154 | 0.913±0.025 | 1.151±0.227 |
| 72 h | 0.506±0.004* | 0.307±0.013** | 0.389±0.912** | 0.784±0.141 |
HCC and MIHA cells were treated with I-ATXP for 24 h, 48 h, and 72 h. The half inhibition concentration IC50 was obtained by the Probit method. The experimental data was obtained by averaging three independent parallel experiments. Compared with MIHA;
*
P < 0.05;
**
P < 0.001.