Table 3.
Clinical criteria used by pediatric computerized clinical decision support (CCDS) systems for sepsis identification.
|
|
Study | |||||||||
|
|
Balamuth et al, 2017 [55] | Cruz et al, 2012 [59] | Dewan et al, 2020 [61] | Eisenberg et al, 2021 [64] (clinician-initiated) | Eisenberg et al, 2021 [64] (automated) | Lloyd et al, 2018 [71] | Stinson et al, 2019 [77] | Vidrine et al, 2020 [81] | Coffman et al, 2018a [58] | Total, n (%b) |
| Temperature | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 9 (69) |
| Capillary refill or perfusion | ✓ | ✓ | ✓ | ✓ |
|
✓ | ✓ | ✓ |
|
7 (54) |
| Mental status | ✓ | ✓ | ✓ | ✓ |
|
✓ | ✓ | ✓ |
|
7 (54) |
| Heart rate | ✓ | ✓ |
|
✓ | ✓ | ✓ | ✓ |
|
|
6 (46) |
| Hypotension | ✓ |
|
✓ | ✓ |
|
✓ | ✓ | ✓ |
|
6 (46) |
| High-risk patient | ✓ | ✓ |
|
✓ |
|
✓ | ✓ |
|
|
5 (38) |
| Pulse assessment |
|
|
✓ | ✓ |
|
✓ | ✓ | ✓ |
|
5 (38) |
| Skin assessment |
|
|
✓ | ✓ |
|
✓ | ✓ | ✓ |
|
5 (38) |
| Respiratory rate |
|
|
|
✓ | ✓ | ✓ | ✓ |
|
|
4 (31) |
| Infection concern, change in clinical or sepsis risk | ✓ |
|
|
✓ |
|
✓ |
|
|
|
3 (23) |
| Blood culture order |
|
|
✓ |
|
|
|
|
✓ |
|
2 (15) |
| Leukocyte count |
|
|
|
|
✓ |
|
|
|
|
1 (8) |
| Cardiac organ dysfunction |
|
|
|
|
✓ |
|
|
|
|
1 (8) |
| Noncardiac organ dysfunction |
|
|
|
|
✓ |
|
|
|
|
1 (8) |
| Change in Pediatric Early Warning Score |
|
|
|
|
|
|
|
|
✓ | 1 (8) |
| Family concern |
|
|
|
|
|
|
|
|
✓ | 1 (8) |
| Vital sign change |
|
|
|
|
|
|
|
|
✓ | 1 (8) |
| Patient risk change |
|
|
|
|
|
|
|
|
✓ | 1 (8) |
aThis study is a conference abstract, and the other 8 studies are journal articles.
bThe percentages were calculated from the number of pediatric studies (n=13).