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. 2022 May 21;10:tkac014. doi: 10.1093/burnst/tkac014

Table 2.

Representative animal models of acute wound infection

Infection model Animal species Modeling methods Microorganisms
Burn infections Rodents and pig Heat source used: boiling water, burning ethanol bath, gas flame, pre-heated double brass blocks, pre-heated single metal plate/bar, etc. Psuedomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii and Candida albicans.
Surgical site infections Mouse, rat and pig Incisional wounds with foreign bodies, subcutaneous injection of foreign bodies and microorganisms into pocket wounds with or without foreign bodies. Staphylococcus aureus, Psuedomonas aeruginosa and methicillin-resistant Staphylococcus aureus.
Skin abrasion wound infections Mouse, rat and rabbit Needle scratch model, blade scrape model, tap striping model, sand paper model and dermatome model. Staphylococcus aureus, Psuedomonas aeruginosa and Candida albicans.
Excisional wound infections Mouse, rat, rabbit and pig Removing the full-thickness skin. Staphylococcus aureus, Psuedomonas aeruginosa, Escherichia coli and methicillin-resistant Staphylococcus aureus.
Lacerated wound infections Guinea pig and rat Non-crushed lacerated wounds and crushed lacerated wounds. Staphylococcus aureus, Streptococcus pyogenes, Psuedomonas aeruginosa, Klebsiella pneumoniae and Proteus mirabilis.