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. Author manuscript; available in PMC: 2023 May 10.
Published in final edited form as: Immunity. 2022 Apr 27;55(5):895–911.e10. doi: 10.1016/j.immuni.2022.04.001

Figure 5. P. aeruginosa can serve as an adjuvant for an allergic response.

Figure 5.

(A) Experimental protocol of PA01 allergic airway inflammation.

(B) Cell frequency of eosinophils (CD45+MHCII–CD11b+CD64-Siglec-F+) and neutrophils (CD45+MHCII–CD11b+CD64-Ly6G+) out of CD45+ cells in the BAL of mice immunized with OVA +/− PA01 or LasB.

(C-E) ELISA of IL-4 (C), IL-5 (D) and IFN-γ amounts in the BAL of mice immunized as in (A).

(F-I) ELISA of total IgE (F), OVA-specific IgE (G), OVA-specific IgG1 (H) and IgG2b (I) amounts in the serum of mice immunized as in (A).

For (B-I) representative of 3 independent experiments, 3–4 mice per group. Data were analyzed by two-tailed unpaired Student’s t test. *p < 0.05; **p < 0.01; ***p < 0.001.

See also Figure S4.