Table 3.
Comparison between Obese and non-obese (pre and post KT) regarding different study parameters
| BMI post-KT | P-value | BMI pre-KT | P-value | |||
|---|---|---|---|---|---|---|
| Non obese (n = 12) | Obese (n = 38) | Non obese (n = 36) | Obese (n = 14) | |||
| No. (%) / Mean ± SD | No. (%) / Mean ± SD | No. (%) / Mean ± SD | No. (%) / Mean ± SD | |||
| Sex | ||||||
| Male | 5 (41.7) | 25 (65.8) | 0.137 | 22 (61.1) | 8 (57.1) | 0.797 |
| Female | 7 (58.3) | 13 (34.2) | 14 (38.9) | 6 (42.9) | ||
| Age (years) | ||||||
| 5–10 | 6 (50) | 2 (5.3) | 0.001٭ | 7 (19.4) | 1 (7.1) | 0.102 |
| 10–15 | 6 (50) | 27 (71.1) | 25 (69.5) | 8 (57.1) | ||
| > 15 | 0 (0) | 9 (23.7) | 4 (11.1) | 5 (35.8) | ||
| Residence | ||||||
| Urban | 5 (41.7) | 26 (68.4) | 0.096 | 22 (61.1) | 9 (64.3) | 0.836 |
| Rural | 7 (58.3) | 12 (31.6) | 14 (38.9) | 5 (35.7) | ||
| Acute rejection › 6 ms | ||||||
| No | 2 (16.7) | 3 (7.9) | 0.377 | 4 (11.1) | 1 (7.1) | 0.675 |
| Yes | 10 (83.3) | 35 (92.1) | 32 (88.9) | 13 (92.9) | ||
| Acute rejection < 6 ms | ||||||
| No | 12 (100) | 26 (68.4) | 0.026٭ | 32 (88.9) | 6 (42.9) | 0.001٭ |
| Yes | 0 (0) | 12 (31.6) | 4 (11.1) | 8 (57.1) | ||
| Chronic rejection | ||||||
| No | 12 (100) | 23 (60.5) | 0.009٭ | 28 (77.8) | 7 (50) | 0.05* |
| Yes | 0 (0) | 15 (39.5) | 8 (22.2) | 7 (50) | ||
| Graft survival | ||||||
| < 5 yrs | 10 (83.3) | 29 (76.3) | 0.047* | 26 (72.2) | 13 (92.9) | 0.114 |
| > 5 yrs | 2 (16.7) | 9 (23.7) | 10 (27.8) | 1 (7.1) | ||
| HTN pre- transplantation | ||||||
| No | 12 (100) | 25 (65.8) | 0.019٭ | 29 (80.6) | 8 (57.1) | 0.090 |
| Yes | 0 (0) | 13 (34.2) | 7 (19.4) | 6 (42.9) | ||
| HTN post-transplantation | ||||||
| No | 8 (66.7) | 18 (47.4) | 0.243 | 21 (58.3) | 5 (35.7) | 0.151 |
| Yes | 4 (33.3) | 20 (52.6) | 15 (41.7) | 9 (64.3) | ||
| Impaired FBG | ||||||
| No | 12(100) | 19 (50) | 0.005٭ | 30 (83.3) | 2 (14.3) | < 0.001٭ |
| Yes | 0 (0) | 19 (50) | 6 (16.7) | 12 (85.7) | ||
| Impaired OGTT | ||||||
| No | 12(100) | 20 (52.6) | 0.007٭ | 29 (80.5) | 2 (14.3) | < 0.001٭ |
| Yes | 0 (0) | 18 (47.4) | 7 (19.5) | 12 (85.7) | ||
| Urinary ACR | ||||||
| Normal | 10 (83.3) | 3 (7.9) | < 0.001٭ | 24 (67.7) | 5 (35.7) | 0.002* |
| High | 2 (16.7) | 35 (92.1) | 12 (33.3) | 9 (64.3) | ||
| Cholesterol (mg/dl) | 193.75 ± 31.94 | 228.16 ± 50.7 | 0.032٭ | 208.31 ± 45.61 | 249.71 ± 45.59 | 0.006٭ |
| TG (mg/dl) | 124.08 ± 20.13 | 155.66 ± 81.58 | 0.193 | 132.42 ± 34.68 | 188.36 ± 119.67 | 0.013٭ |
| LDL (mg/dl) | 127.42 ± 31.15 | 160.24 ± 26.41 | 0.001٭ | 144.42 ± 30.66 | 172.79 ± 20.17 | 0.002٭ |
| HDL (mg/dl) | 65.08 ± 15.23 | 48.89 ± 10.64 | 0.000٭ | 55 ± 14.17 | 47.07 ± 10.64 | 0.065 |
| HbA1c (%) | 5.13 ± 0.2 | 5.58 ± 0.46 | 0.003٭ | 5.31 ± 0.3 | 5.89 ± 0.44 | 0.001 |
BMI Body Mass Index, SD Standard Deviation, KT Kidney Transplantation, FBG Fasting Blood Glucose, TG Triglycerides, OGTT Oral Glucose Tolerance test, ACR Albumin Creatinine Ratio, HDL High Density Lipoprotein, LDL Low Density Lipoprotein, HbA1c Glycosylated Hemoglobin
*p-value less than 0.05 and it is statistically significant