Table 1.
Active Collaboratory demonstration projects at the outset of the pandemic
| Acronym (ClinicalTrials.gov identifier) | Trial name | Therapeutic area |
|---|---|---|
| Implementation phase | ||
| ACP PEACE (NCT03609177) | Improving Advance Care Planning: Promoting Effective and Aligned Communication in the Elderly | Cancer |
| EMBED (NCT03658642) | Pragmatic Trial of User-Centered Clinical Decision Support to Implement Emergency Department-Initiated Buprenorphine for Opioid Use Disorder | Opioid use disorder |
| GGC4H (NCT04040153) | Guiding Good Choices for Health: Testing Feasibility and Effectiveness of Universal Parent-Focused Prevention in Three Healthcare Systems | Adolescent behavioral health |
| HiLo (NCT04095039) | Pragmatic Trial of Higher vs. Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis | Hemodialysis |
| ICD-Pieces (NCT02587936) | Improving Chronic Disease Management with Pieces | Chronic kidney disease, diabetes and hypertension |
| Nudge (NCT03973931) | Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications | Cardiovascular disease |
| PRIM-ER (NCT03424109) | Primary Palliative Care for Emergency Medicine | Palliative care |
| Pilot phase | ||
| BackInAction (NCT04982315) | Pragmatic Trial of Acupuncture for Chronic Low Back Pain in Older Adults | Chronic pain |
| FM-TIPS (NCT04683042) | Fibromyalgia TENS in Physical Therapy Study | Fibromyalgia/chronic pain |
| NOHARM (NCT04570371) | Nonpharmacologic Options in Postoperative Hospital-based and Rehabilitation Pain Management | Post-surgical pain |
| OPTIMUM (NCT04129450) | Group-based Mindfulness for Patients with Chronic Low Back Pain in the Primary Care Setting | Chronic pain |
| Completed enrollment | ||
| PROVEN (NCT02612688) | Pragmatic Trial of Video Education in Nursing Homes | Advanced care planning |
| SPOT (NCT02326883) | Suicide Prevention Outreach Trial | Behavioral health |
| TSOS (NCT02655354) | A Policy-Relevant U.S. Trauma Care System Pragmatic Trial for PTSD and Comorbidity (Trauma Survivors Outcomes and Support) | Behavioral health |