. 2022 May 21;23:482. doi: 10.1186/s12891-022-05427-1

Table 2.

Comparison of serum BTMs levels in each group

Parameters	Normal ^a (n = 27)	Osteopenia ^b (n = 27)	Osteoporosis ^c (n = 27)	Severe osteoporosis ^d (n = 27)	P-value
CTX (ng/ml)	0.29 ± 0.14	0.52 ± 0.16^*	0.65 ± 0.20^*	0.78 ± 0.23^*#	< 0.0001
PINP (ng/ml)	44.00 ± 12.55	48.30 ± 15.95	62.11 ± 21.04^*	65.04 ± 23.73^*	< 0.0001
OC (ng/ml)	8.33 ± 4.18	10.41 ± 4.67	17.70 ± 8.26^*#	18.75 ± 10.45^*#	< 0.0001

Parameters

Normal ^a (n = 27)

Osteopenia ^b (n = 27)

Osteoporosis ^c (n = 27)

Severe osteoporosis ^d (n = 27)

P-value

CTX

(ng/ml)

0.29 ± 0.14

0.52 ± 0.16^*

0.65 ± 0.20^*

0.78 ± 0.23^*#

< 0.0001

PINP (ng/ml)

44.00 ± 12.55

48.30 ± 15.95

62.11 ± 21.04^*

65.04 ± 23.73^*

< 0.0001

(ng/ml)

8.33 ± 4.18

10.41 ± 4.67

17.70 ± 8.26^*#

18.75 ± 10.45^*#

< 0.0001

Data are presented as the mean ± SD for CTX, PINP and OC

^a T-score ≥ -1.0

^b T-score < -1.0 and > -2.5

^c At least one of the following criteria fulfilled: (a) T-score ≤ -2.5; (b) femoral neck fragile fracture)

^d Fragility fracture with a T-score ≤ -2.5

^*P < 0.05, compared with normal group

^#P < 0.05, compared with osteopenia group

^▲ P < 0.05, compared with OP group

CTX C-terminal telopeptide of type I collagen, PINP type I procollagen N-terminal propeptide, OC osteocalcin