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. 2022 May 21;17:29. doi: 10.1186/s13722-022-00310-9

Table 2.

Multiple logistic regression analyses

Covariablesa Main analysis (n = 1943) Censored participants (n = 2900) Excluding participants with out-patient cessation (n = 1834)
Adjusted OR (95% CI) P P for trend Adjusted OR (95% CI) P P for trend Adjusted OR (95% CI) P P for trend
Age ≥ 65 years 1.78 (1.40–2.28)  < 0.001 1.29 (0.98–1.69) 0.073 1.72 (1.34–2.20)  < 0.001
Male 1.04 (0.73–1.49) 0.839 1.10 (0.79–1.51) 0.579 1.02 (0.71–1.46) 0.920
≥ 2 comorbiditiesb 1.25 (1.01–1.53) 0.037 1.17 (0.97–1.41) 0.099 1.27 (1.03–1.58) 0.026
Daily cigarette smoking > 20 1.09 (0.86–1.38) 0.487 0.75 (0.62–0.90) 0.003 1.09 (0.85–1.39) 0.492
FTND
  < 4 Reference Reference Reference
 4 to 6 0.49 (0.34–0.69)  < 0.001 0.69 (0.47–1.01) 0.056 0.45 (0.32–0.64)  < 0.001
  ≥ 7 0.28 (0.19–0.42)  < 0.001 0.50 (0.30–0.84) 0.009 0.27 (0.18–0.41)  < 0.001
Self-motivated 1.19 (0.95–1.50) 0.139 0.67 (0.49–0.91) 0.012 1.20 (0.96–1.54) 0.098
Discharge diagnosis
 Others Reference Reference Reference
 Cancer 2.18 (1.66–2.86)  < 0.001 1.67 (1.32–2.13)  < 0.001 2.19 (1.67–2.87)  < 0.001
 CAD/HF 1.40 (1.04–1.88) 0.028 1.24 (0.95–1.62) 0.110 1.35 (0.99–1.85) 0.058
 COPD/pneumonia 1.58 (0.96–2.61) 0.073 1.32 (0.82–2.12) 0.252 1.45 (0.83–2.56) 0.195
ICU admission 2.82 (2.14–3.73)  < 0.001 2.41 (1.89–3.06)  < 0.001 2.84 (2.13–3.78)  < 0.001
Hospitalization > 4 days 1.43 (1.15–1.77) 0.001 1.19 (0.98–1.45) 0.076 1.46 (1.17–1.82) 0.001
Cessation medications
 No use Reference Reference Reference
 NRT 1.12 (0.74–1.68) 0.599 1.05 (0.73–1.52) 0.784 1.10 (0.70–1.73) 0.684
 Non-NRT 1.60 (0.89–2.86) 0.115 1.42 (0.85–2.38) 0.180 1.83 (0.93–3.59) 0.081
 NRT and non-NRT 0.80 (0.42–1.51) 0.484 0.81 (0.46–1.45) 0.485 0.97 (0.48–1.97) 0.927
Number of in-hospital counseling  < 0.001 0.010 0.012
 1 Reference Reference Reference
 2 1.44 (1.05–1.98) 0.025 1.21 (0.92–1.61) 0.180 1.43 (1.03–1.98) 0.034
  ≥ 3 2.02 (1.27–3.22) 0.003 1.82 (1.21–2.73) 0.004 1.62 (0.98–2.66) 0.059

CAD coronary artery disease, CI confidence interval, COPD chronic obstructive pulmonary disease, FTND Fagerstrom test for nicotine dependence, HF heart failure, ICU intensive care unit, NRT nicotine replacement therapy, OR odds ratio

aReferences for covariables: age (≥ 65 versus < 65), sex (male versus female), number of comorbidities (≥ 2 versus < 2), number of cigarettes smoked daily (> 20 versus ≤ 20), FTND score (≥ 7 and 4–6 versus < 4), motivation (self-motivated versus not self-motivated), main discharge diagnosis (cancer, CAD/HF, COPD/pneumonia versus without), ICU admission (yes versus no), length of hospital stay (> 4 days versus ≤ 4 days), and cessation medications (NRT, non-NRT, and both versus no)

bComorbidities include cardiovascular disease, cancer, cerebral vascular disease, diabetes mellitus, hypertension, liver disease, respiratory system disease, and renal disease