Skip to main content
. 2022 May 21;16:12. doi: 10.1186/s13030-022-00241-6

Table 3.

A summary of the quality of the evidence using the GRADE approach

Quality assessment Summary of findings
No of studies Risk of bias Imprecision Inconsistency Indirectness Publication bias No of participants Pooled standardised mean difference (95% confidence intervals) Quality of evidence
Pain for intermediate term
2 Serious risk of bias, indicating downgraded on level due to there was more than 25% of participants from studies

Very serious imprecision due to very limited sample sizes (fewer than 400 participants), and no significant difference rate down two levels

Significant

Very Serious

Downgraded two levels due to I2 > 75%, rate down two levels

Not serious

Indirectness, do not downgrade

Undetected 300

-1.38

(-2.78 to 0.02)

⨁◯◯◯

VERY LOW

Pain for long term
2 Serious risk of bias, indicating downgraded on level due to there was more than 25% of participants from studies

Very serious imprecision due to very limited sample sizes (fewer than 400 participants), and no significant difference rate down two levels

Significant

Serious

Downgraded one level due to I2 > 50%, rate down one level

Not serious

Indirectness, do not downgrade

Undetected 300

-1.01

(-1.92 to -0.10)

⨁◯◯◯

VERY LOW

Disability/functional status for intermediate term
3 Serious risk of bias, indicating downgraded on level due to there was more than 25% of participants from studies

Serious imprecision due to very limited sample sizes (fewer than 400 participants), rate down one level

Significant

Very Serious

Downgraded two levels due to I2 > 75%, rate down two levels

Serious

Downgraded one level due to different sample

Undetected 333

-0.76

(-1.46 to -0.07)

⨁◯◯◯

VERY LOW

Disability/functional status for long term
2 Serious risk of bias, indicating downgraded on level due to there was more than 25% of participants from studies

Serious

imprecision due to very limited sample sizes (fewer than 400 participants), rate down one level

Significant

Serious

Downgraded one level due to I2 > 50%, rate down one level

Not serious

Indirectness, do not downgrade

Undetected 300

-8.48

(-11.47 to -5.49)

⨁◯◯◯

VERY LOW

Fear of physical activity for intermediate term
2 Serious risk of bias, indicating downgraded on level due to there was more than 25% of participants from studies

Serious

imprecision due to very limited sample sizes (fewer than 400 participants), rate down one level

Significant

Serious

Downgraded one level due to I2 > 50%, rate down one level

Not serious

Indirectness, do not downgrade

undetected 300

-3.01

(-5.14 to -0.88)

⨁◯◯◯

VERY LOW

Fear of physical activity for long term
2 Serious risk of bias, indicating downgraded on level due to there was more than 25% of participants from studies

Serious

imprecision due to very limited sample sizes (fewer than 400 participants), rate down one level

Significant

Very Serious

Downgraded two levels due to I2 > 75%, rate down two levels

Not serious

Indirectness, do not downgrade

Undetected 300

-3.56

(-6.43 to -0.68)

⨁◯◯◯

VERY LOW