Table 2.

Spearman correlation analyses between PCSK9 and metabolism and inflammation makers according to diabetes status

	Whole cohort (n = 1027)		DM (n = 277)		Non-DM (n = 750)
	r	P	r	P	r	P
Metabolism related markers
Body mass index	0.021	0.507	− 0.020	0.747	0.034	0.355
Fasting glucose	− 0.038	0.229	− 0.133	0.031	− 0.018	0.622
HbA1C	0.040	0.207	− 0.048	0.438	0.062	0.096
Total cholesterol	0.044	0.164	0.038	0.536	0.047	0.210
LDL-C	0.005	0.872	− 0.039	0.525	0.022	0.549
HDL-C	− 0.081	0.011	0.023	0.706	− 0.120	0.001
Triglycerides	0.146	< 0.001	0.214	< 0.001	0.111	0.003
Lipoprotein(a)	0.075	0.019	0.048	0.438	0.089	0.017
Inflammatory marker
hs-CRP	0.112	< 0.001	0.205	0.001	0.076	0.041

PCSK9 proprotein convertase subtilisin/kexin type 9, DM diabetes mellitus, non-DM non-diabetes mellitus, HbA1C hemoglobin A1c, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, hs-CRP high-sensitivity C reactive protein, sCD40L soluble CD40 ligand