Table 4.
Spearman correlation analyses between PCSK9 and platelet reactivity parameters according to diabetes status and P2Y12 inhibitor stratification
| Whole cohort (n = 1027) | DM (n = 277) | Non-DM (n = 750) | ||||
|---|---|---|---|---|---|---|
| r | P | r | P | r | P | |
| Ticagrelor | n = 563 | n = 143 | n = 420 | |||
| MPA at 7 days | 0.144 | 0.012 | 0.236 | 0.041 | 0.111 | 0.094 |
| MAADP at 7 days | 0.080 | 0.228 | 0.336 | 0.013 | 0.033 | 0.664 |
| Clopidogrel | n = 464 | n = 134 | n = 330 | |||
| MPA at 7 days | 0.100 | 0.113 | − 0.078 | 0.586 | 0.190 | 0.110 |
| MAADP at 7 days | − 0.048 | 0.546 | − 0.172 | 0.160 | − 0.041 | 0.667 |
PCSK9 proprotein convertase subtilisin/kexin type 9, DM diabetes mellitus, Non-DM non-diabetes mellitus, MPA maximal platelet aggregation, MAADP maximum amplitude of adenosine diphosphate-induced platelet-fibrin clots