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. 2022 May 20;21:80. doi: 10.1186/s12933-022-01519-3

Table 4.

Spearman correlation analyses between PCSK9 and platelet reactivity parameters according to diabetes status and P2Y12 inhibitor stratification

Whole cohort (n = 1027) DM (n = 277) Non-DM (n = 750)
r P r P r P
Ticagrelor n = 563 n = 143 n = 420
 MPA at 7 days 0.144 0.012 0.236 0.041 0.111 0.094
 MAADP at 7 days 0.080 0.228 0.336 0.013 0.033 0.664
Clopidogrel n = 464 n = 134 n = 330
 MPA at 7 days 0.100 0.113 − 0.078 0.586 0.190 0.110
 MAADP at 7 days − 0.048 0.546 − 0.172 0.160 − 0.041 0.667

PCSK9 proprotein convertase subtilisin/kexin type 9, DM diabetes mellitus, Non-DM non-diabetes mellitus, MPA maximal platelet aggregation, MAADP maximum amplitude of adenosine diphosphate-induced platelet-fibrin clots