Table 1.

Participant demographic and clinical information

N (Patients) a	WML		p-values
	WML (−) 277 (52.7)	WML (+) 249 (47.3)
Gender a
Male	59 (45.7)	70 (54.3)	0.074
Female	218 (54.9)	179 (45.1)
Age b	40.30 ± 12.57	51.43 ± 11.93	0.010*
H. pylori (+) a	137 (26.0)	178 (33.8)	0.026*
Diabetes mellitus (+) a	31 (5.9)	41 (7.8)	0.079
Hypertension (+) a	60 (11.4)	112 (21.3)	0.001*

^a: n (%), ^b: mean ± standard deviation

WML White matter lesion, H. pylori Helicobacter pylori

* Mean difference is significant at the 0.05 level