Table 1.
Baseline characteristics
| N | ||
|---|---|---|
| Age (years) | 28 | 52.5 (22–75; 20.0) |
| Sex (female), n (%) | 28 | 26 (92.9) |
| Weight (kg) | 28 | 75.5 (50–105;24.3) |
| Disease duration (months) | 28 | 31.5 (4–180) |
| Medication | ||
| Methotrexate, n (%) | 28 | 16 (57.1) |
| Prednisolone, n (%) | 28 | 23 (82.1) |
| Biologics naïve, n (%) | 25a | 15 (60.0) |
| Clinical parameters | ||
| DAS28 (CRP) | 28 | 4.61 (2.65–6.49; 1.75) |
| Tender joint count (28-TJC) | 28 | 7.0 (0–22;8.75) |
| Swollen joint count (28-SJC) | 28 | 2.5 (0–9;4.0) |
| VAS patient (0–10 cm) | 28 | 6.0 (2.4–10;3.0) |
| VAS physician (0–10 cm) | 28 | 4.0 (1.9–8.5;1.7) |
| Morning stiffness (min.) | 28 | 30 (0–240;63.75) |
| Laboratory parameters | ||
| ESR (mm/h) | 28 | 27 (8–66;21.0) |
| CRP (mg/l) | 27b | 5.4 (0.3–52;17.4) |
| Fluorescence optical imagingc | ||
| P1 | 28 | 1.5 (0–16;9.25) |
| P2 | 28 | 19.5 (0–36;14.5) |
| P3 | 28 | 1.0 (0–20;3.75) |
| PVM | 28 | 5 (0–27;6.25) |
| Musculoskeletal ultrasound (US7 Score) | ||
| GS US7 synovitis (range 0–39) | 28 | 11 (4–22;8.25) |
| PD US7 synovitis (range 0–39) | 28 | 2.0 (0–17;3.0) |
| GS US7 tenosynovitis (range 0–5) | 28 | 0.5 (0–3;1.0) |
| PD US7 tenosynovitis (range 0–15) | 28 | 0 (0–2;1.0) |
Data represent median (min–max; interquartile range) unless otherwise stated. aStatus for 3 patients unknown; bone sample not analysed; csum scores of both hands. DAS28 disease activity score of 28 joints, CRP C-reactive protein, VAS visual analogue scale, ESR erythrocyte sedimentation rate, GS grey scale, PD power Doppler, P phase, PVM prima vista mode, US7 ultrasound score of 7 selected joints